师资队伍

  • 两院院士
  • 高层次人才
  • 在职教师
  • 荣休教师

董秀琴

办公地点:化北-409

联系电话:

电子邮箱:xiuqindong@whu.edu.cn; xiuqindong-chem@whu.edu.cn

团队主页: http://wanglab.whu.edu.cn/

个人简介

73882必赢游戏欢迎光临教授,博士生导师,国家级青年人才项目入选者。围绕开发新型手性膦配体和高效不对称催化体系展开研究工作,主持3项国家级基金(2项面上项目,1项青年基金)和3项省部级基金(含湖北省杰出青年项目),以第一作者或通讯作者(含共同)在Acc. Chem. Res.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、CCS Chem.、Fundamental Res.、Chem. Sci.、ACS Catal.、Org. Lett.、Chem. Commun.、Org. Chem. Front.等杂志上发表论文七十余篇,其中20篇被评述杂志Synfacts进行正面评价,2篇被选为VIP文章,4篇被选为Hot paper,3篇被作为封面,1篇被J. Am. Chem. Soc.的Spotlights予以积极评价,1篇被《有机化学》亮点评述。入选2017年度湖北省“楚天学者计划”,2019年-2025年任第三届和第四届《Chinese Chemical Letters》青年编委会委员,获得2020年73882必赢游戏欢迎光临本科优秀教学业绩奖和学院青年教师教学竞赛一等奖。

教育经历

2003.09-2007.07 黄冈师范学院化学学院 大学本科

2007.09-2012.07 73882必赢游戏欢迎光临 博士研究生

工作经历

2012.09-2014.09 香港科技大学化学系博士后

2015.01-2023.05 大学73882必赢游戏欢迎光临副教授

2023.05-至今 73882必赢游戏欢迎光临教授

研究方向

1. 发展新型手性膦配体及其在不对称催化反应中的应用研究、2. 开发不对称协同催化体系及其在催化反应中的应用研究3. 运用不对称催化反应高效构建手性药物或生物活性分子关键中间体

代表成果

1. Zhi-Yuan Yi, Lu Xiao, Xin Chang, Xiu-Qin Dong,* and Chun-Jiang Wang,* Iridium-Catalyzed Asymmetric Cascade Allylation/Retro-Claisen Reaction, J. Am. Chem. Soc., 2022, 144, 20025.

2. Xi-Shang Sun, Xin-Yu Diao, Xiu-Qin Dong,* and Chun-Jiang Wang,* Base- promoted cascade β-F-elimination/electrocyclization/Diels-Alder/retro-Diels-Alder reaction: efficient access to δ-carboline derivatives, Chem. Sci., 2022, 13, 10448.

3. Gongyi Liu, Lini Zheng, Kui Tian, Haifeng Wang, Lung Wa Chung, Xumu Zhang* and Xiu-Qin Dong,* Ir-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope Investigations and Mechanistic Studies, CCS Chem., 2022, DOI: 10.31635/ccschem.022.202101643.

4. Lu Xiao, Bo Li, Fan Xiao, Cong Fu, Liang Wei, Yanfeng Dang*, Xiu-Qin Dong,* and Chun-Jiang Wang,* Stereodivergent synthesis of enantioenriched azepino[3,4,5-cd]-indoles via cooperative Cu/Ir-catalyzed asymmetric allylic alkylation and intramolecular Friedel–Crafts reaction, Chem. Sci., 2022, 13, 4801.

5. Zhengyu Han, Gang Liu, Xuanliang Yang, Xiu-Qin Dong,* and Xumu Zhang,* Enantiodivergent Synthesis of Chiral Tetrahydroquinoline Derivatives via Ir-Catalyzed Asymmetric Hydrogenation: Solvent-Dependent Enantioselective Control and Mechanistic Investigations, ACS Catal., 2021, 11, 7281.

6. Qingyang Zhao,* Caiyou Chen, Jialin Wen, Xiu-Qin Dong,* Xumu Zhang,* Noncovalent Interaction-assisted Ferrocenyl Phosphine Ligands in Asymmetric Catalysis, Acc. Chem. Res., 2020, 53, 1905.

7. Yuanhua Liu, Zhiyuan Yi, Xuanliang Yang, Heng Wang, Congcong Yin, Minyan Wang,* Xiu-Qin Dong,* and Xumu Zhang,* Efficient Access to Chiral 2- Oxazolidinones via Ni-Catalyzed Asymmetric Hydrogenation: Scope Study, Mechanistic Explanation, and Origin of Enantioselectivity, ACS Catal., 2020, 10, 11153

8. Zhengyu Han, Gang Liu, Rui Wang, Xiu-Qin Dong,* Xumu Zhang,* Highly Efficient Ir-Catalyzed Asymmetric Hydrogenation of Benzoxazinones and Derivatives with Brønsted Acid Cocatalyst, Chem. Sci., 2019, 10, 4328.

9. Gongyi Liu, Heng Zhang, Yi Huang, Zhengyu Han, Gang Liu, Yuanhua Liu; Xiu-Qin Dong,* Xumu Zhang,* Efficient synthesis of chiral 2,3-dihydrobenzo[b]thiophene 1,1-dioxides via Rh-catalyzed hydrogenation, Chem. Sci., 2019, 10, 2507.

10. Caiyou Chen, Zhefan Zhang, Shicheng Jin, Xiangru Fan, Mingyu Geng, Yan Zhou, Songwei Wen, Xinrui Wang, Lung Wa Chung,* Xiu-Qin Dong,* Xumu Zhang,* Enzyme-Inspired Chiral Secondary-Phosphine-Oxide Ligand with Dual Noncovalent Interactions for Asymmetric Hydrogenation, Angew. Chem. Int. Ed., 2017, 56, 6808.

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